右美托咪啶复合瑞芬太尼在超声胃镜中的应用

Application of dexmedetomidine combined with remifentanil in ultrasonic gastroscopy

目的:探讨使用右美托咪啶复合瑞芬太尼进行静脉麻醉在超声胃镜诊治中的可行性、有效性及安全性。方法:选取2015年10月至2017年10月南京市鼓楼医院接受超声胃镜检查的患者,随机将其分为研究组与对照组。对照组患者仅接受瑞芬太尼的辅助治疗,研究组患者在瑞芬太尼基础上接受右美托咪啶辅助治疗。对比2组患者的检查满意度、手术时间、术中知晓率、苏醒时间、不良反应发生情况。结果:研究组患者的检查满意度明显高于对照组(P<0.05),不良反应发生率明显低于对照组(P<0.05);研究组患者的呼吸抑制发生率以及麻醉药物消退时间明显小于对照组(P<0.05)。结论:右美托咪啶复合瑞芬太尼应用于胃镜超声辅助检查时能明显提高患者的检查满意度,安全有效,值得推荐使用。

Objective To investigate the feasibility,effectiveness and safety of intravenous anesthesia with dexmedetomidine and remifentanil in the diagnosis and treatment of gastroscopy.Methods Patients who underwent ultrasonic gastroscopy in Nanjing Drum Tower Hospital from October 2015 to October 2017 were randomly divided into the study group and control group.The control group was only treated with remifentanil while the study group was treated with dexmedetomidine combined with remifentanil.The satisfaction with examination,duration of operation,intraoperative awareness rate,recovery time and the incidence of adverse reactions were compared between the two groups.Results The satisfaction rate of the study group was significantly higher than that of the control group (P<0.05). The incidence of adverse reactions in the study group was significantly lower than that in the control group (P<0.05). The respiratory depression rate and the extinction time of anesthetics in the study group were significantly lower/shorter than those in the control group (P<0.05). Conclusion The combined use of dexmedetomidine combined with remifentanil can significantly improve the patient's satisfaction with examination,safe and effective.