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前列腺神经内分泌癌研究新进展 被引量:6

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摘要 前列腺神经内分泌癌由一大类伴有神经内分泌分化的原发性前列腺肿瘤组成,多见于去势治疗抵抗的前列腺癌患者中,常伴有TMPRSS2-ERG基因的融合及AURKA等基因的扩增。由于大部分前列腺神经内分泌癌侵袭性强且预后差,因此应引起临床及病理医生的高度重视,本文将对前列腺神经内分泌癌的起源、关键分子改变及形态学谱系进行详细阐述。
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 2019年第1期73-75,共3页 Chinese Journal of Urology
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