摘要
In human genetics,genome-wide association study (GWAS)is a commonly used method for discovering genes and genetic variants contributing to human traits,usually through statistical examination of the associations between whole-genome sequence variants and one specific trait.The first effort in human GWAS,using genotyping data of 96 patients and 50 healthy controls,successfully identified one gene associated with age-related macular degeneration (Haines et al.,2005).
