副乳腺癌37例临床诊治分析

Clinicopathological analysis of 37 cases of accessory breast cancer

目的探讨副乳腺癌的临床病理特征、诊断、综合治疗及预后特点。方法对天津医科大学肿瘤医院2005年12月至2017年8月收治的37例副乳腺癌患者的临床病理资料进行回顾性分析。结果本组病例中12例患者行保留乳房的肿物局部广泛切除及腋窝淋巴结清扫术;5例患者行肿物区段切除术;19例患者行乳腺癌改良根治术或根治术;1例患者拒绝手术治疗。组织学类型中最常见的为浸润性导管癌26例(70.3%),腺癌4例,其他类型癌7例。病理分期Ⅱ期24例,Ⅰ期8例,Ⅲ期3例,Ⅳ期2例。全部患者随访1~12年,中位随访时间6年,随访率100%。随访至2017年12月,7例发生远处转移并死于该病,余30例存活。结论副乳腺癌是一种罕见且预后较差的恶性肿瘤,应采取以手术为主的综合治疗。

Objective To explore the clinicopathological characteristics,diagnosis,treatment and prognosis of accessory breast cancer. Methods Clinical and pathological data of 37 accessory breast cancer patients from Dec 2005 to Aug 2017 were reviewed. Results 12 patients underwent breast-conserving local wide excision plus axillary lymph node dissection.5 cases were treated by segmental resection and 19 patients by Auchincloss or Halsted mastectomy;One patient abandoned surgery.The most common histological type of accessory breast cancer was infiltrating ductal carcinoma (26 cases,70.3%) followed by adenocarcinoma (4 cases) and miscellaneous type (7 cases).The most common AJCC pathological stages were stage Ⅱ(n=24,65%),Ⅰ (n=8),Ⅲ (n=3) and Ⅳ (n=2).The median follow-up time was 6 (1-12) years,the followup rate was 100%.Until Dec 2017,7 patients died from metastasis and the others were alive. Conclusions Accessory breast cancer is rare and with poor prognosis.The diagnosis depends on clinical manifestations,imaging and pathology.Surgery is the mainstay therapy,adjuvant chemo therapy is recommanded.