摘要
设计、合成了一种基于新型萘环稠合硼氟二吡咯化合物(BODIPY)5的氟离子比率计量型和荧光猝灭型分子探针.通过紫外-可见光谱实验发现,该探针在氟离子存在时光谱红移100 nm,进入近红外区域,可用于肉眼比色检测.荧光光谱分析表明,氟离子可促使荧光猝灭.细胞成像研究表明探针分子5可在活体细胞中专一性地识别氟离子.
A colorimetric and fluorescent turn-off chemosensor for fluoride based on novel naphthalene-fused boron dipyrromethene (BODIPY) 5 was designed and synthesized. In various anions, only upon addition of fluoride, the UV-Vis absorption peak of probe 5 red-shifted 100 nm, reaching the near infrared (NIR) region. Thus, it can be used as naked-eye detector for fluoride ion. In the fluorescence test, upon addition of fluoride, the fluorescence of probe 5 quenched significantly. Confocal fluorescence microscopy experiments demonstrate that 5 can be used for monitoring fluoride in living cells.
作者
周建平
吴保庚
周志宽
田蒋为
袁爱华
Zhou Jianping;Wu Baogeng;Zhou Zhikuan;Tian Jiangwei;Yuan Aihua(School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003;Department of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing 211198)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2019年第2期406-411,共6页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(Nos.21501073,21775166,51672114)
中国博士后基金(No.2017M621662)资助项目~~
