N,N-二(2-吡啶甲基)胺基三聚茚衍生物的合成及对铜离子、镍离子的选择性识别

N,N-Bis（2-pyridylmethyl）amine-Based Truxene Derivative as a Highly Sensitive Fluorescence Sensor for Cu2+ and Ni2+ Ion

以二(2-吡啶甲基)胺(DPA)和三聚茚为原料,设计合成了一种"turn-off"型荧光探针化合物6,表征了其结构,研究了它对不同金属离子的识别作用.结果表明,化合物6对Cu^2+和Ni^2+具有较高的灵敏性和选择性,在N,N-二甲基甲酰胺(DMF)/H2O(V/V=8/2,pH=7.0)溶液中对Cu^2+、Ni^2+显示出荧光淬灭效应,且对Cu^2+检测几乎不受其他金属离子的干扰;高分辨质谱证明化合物6与Cu^2+、Ni^2+结合计量比为1:1;化合物6对Cu^2+的检测极限可低至28 nmol/L,对Ni^2+的检测极限可低至41 nmol/L,检测极限均低于世界卫生组织(WHO)规定的饮用水中两种离子最大含量,有潜在的应用价值.

A new turn-off probe 6 was synthesized from bis(pyridin-2-ylmethyl)amine and truxene derivatives, and its structure was confirmed by 1H NMR and HRMS. The recognition behaviors of 6 to various metal ions were investigated and the results show that 6 exhibited good selectivity and high sensitivity to Cu^2+ and Ni^2+ with good anti-interference. The probe 6 presented apparent fluorescence quenching in DMF/H2O (V/V=8/2, pH=7.0) solution toward Cu^2+ and Ni^2+. HRMS analysis showed a 1:1 binding stoichiometry between 6 and Cu^2+ or Ni^2+. The detection limit for Cu^2+ and Ni^2+ was calculated to be 28 and 41 nmol/L, respectively. The detection limit of 6 for Cu^2+ and Ni^2+ was far lower than the maximum allowable level of World Health Organization (WHO) limit for drinking water.