摘要
报道了一种简单实用的磺酰胺绿色合成方法,以硝基苯和磺酰氯为原料,铁粉为唯一还原剂,纯水作为溶剂.该反应具有反应成本低,溶剂环境友好,反应条件温和,底物适用性广的优点.
A simple and practical route for construction of various sulfonamides from nitroarenes and sulfonyl chlorides with iron powder as the sole reductant in water (green solvent) under open-air conditions was developed. The protocol features low-cost, environmentally benign solvent, mild reaction conditions and wide broad substrate scope.
作者
岳会兰
鲍鹏丽
王雷雷
吕晓霞
杨道山
王桦
魏伟
Yue Huilan;Bao Pengli;Wang Leilei;Lü Xiaoxia;Yang Daoshan;Wang Hua;Wei Wei(Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Qinghai 810008;School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2019年第2期463-468,共6页
Chinese Journal of Organic Chemistry
基金
Project supported by the International Cooperation Project of Qinghai Province(Nos.2018-HZ-806,2017-HZ-806)
the Qinghai Key Laboratory of Tibetan Medicine Research(No.2017-ZJ-Y11)
the Natural Science Foundation of Shandong Province(Nos.ZR2018MB009,ZR2016JL012)
the National Natural Science Foundation of China(Nos.21302109,21302110,21601106)~~
关键词
水
绿色有机合成
磺酰胺
磺酰氯
铁粉
water
green organic synthesis
sulfonamides
sulfonyl chlorides
iron power
