心肌组织超声背向散射定量评价Graves’病心肌病变

Quantitative Analysis of Myocardial Tissue by Using Ultrasonic Backscatter in Patients with Graves' Disease.

目的:应用心肌组织超声背向散射定量新技术评价Graves’病患者心肌病变的特点和应用价值。方法:研究对象为新诊断的Graves’病的患者26例。另设17位正常人为对照组。每个切面分成室间隔、前壁、侧壁及后壁4个节段,分别测量两组平均组织整合后散射积分（integrated backscatter IB）及其周期性变化曲线的形态和幅度（characteristics curve of IB,CVIB）。结果:正常组心肌组织整合后散射积分周期性变化曲线为随心动周期呈周期性变化的正弦波,舒张末期为最高值,收缩末期为最低值,形态较规则。病例组心肌组织整合后散射积分周期性变化曲线也为随心动周期呈周期性变化的正弦波。病例组所有节段的CVIB均高于正常人（P<0.05）,而所有节段的IB与正常人无差异（P>0.05）。结论:Graves’病患者心肌所有节段心肌组织密度与正常人无显著差别,而心肌组织密度在心动周期中的变化均高于正常人。

: To evaluate the tissue characteristics of cardiomyopathy. Methods: 26 in Graves' disease. patients with Graves'disease (aged37.38±9.88 years) and 17 normal subjects (aged 33.47±9.13 years) were selected. Integrated backscatter (IB), characteristics curve of IB in cardiac cycle and its variation (CVIB) in the ventricular septum, left ventricular anterior wall, lateral wall and posterior wall were analyzed in the short - axis views at the apical level, the papillary level and the mitral level by Hewlett Packard sonos 5500 ultrasound system with backscatter imaging system. Results: The shape of characteristics curve of IB in cardiac cycle was similar to sine wave both in patients and in normal subjects. The CVIB in all segment of left ventricular in Graves 'disease was higher than that in normal(P<0.05), but IB in all segment of left in Graves'disease was as same as that in normal (P >0. 05). Conclusion: The myocardial tissue density in Graves' disease is as that in same as normal, and the variation of myocardial tissue density in cardiac cycle in Graves'disease is higher than that in normal.