硒蛋白对心血管疾病辅助治疗的临床评价

Clinical evaluation of the supplementary treatment of selenium protein for cardiovascular disease

目的 评价有机硒辅助治疗心血管疾病的临床效果。方法 患者分成两组 ,45例患者在常规治疗的基础上加服有机硒 ,15例患者只进行常规治疗。分别测出两组患者治疗前后的血脂系列和血糖 ,并进行对比分析。结果 45例患者给予硒蛋白并含有硒化类胡萝卜素制剂辅助治疗后 ,高密度脂蛋白 (HDL )显著提高 ,低密度脂蛋白 (L DL )、甘油三酯 (TG)及总胆固醇 (TC)显著下降 ,并对无糖尿病的心血管病患者血糖影响不大。其效应大大优于对照组。结论 动脉粥样硬化、冠心病等扩张性心肌病的发病原因之一则为低硒 ,有机硒在预防和控制心血管疾病的发展中有一定的作用。

Objective Evaluating the clinical effect of supplementary treatment of selenium protein for cardiovascular disease.Methods The patients were divided into two groups,45 patients in one group not only received routine treatment but took selenium protein as a supplementary treatment;15 patients in another group only receivd the routine treatment.Then the serum lipid and blood glucose of all the patients in each group were measured before and after the treatment separately;the results were compared and analyzed (including contrasting t test results in each group and between the two groups).Results Treatment groups had a noted improvement in their blood lipid data,45 cases who received selenium protein and selenium containing carotenoid preparations had a good increase in HDL (P<0 01),but a decrease in LDL,triglyceride (TG) and total cholesterol (TC),not very affecting the blood sugar level in those cardiovascular cases without diabetes mellitus.Conclusion Lack of selenium is one factor for the incidence of dilated cardiomyopathy,such as atherosclerosis and coronary heart disease,so the organic selenide exerts a preventive and controlling action on cardiovascular disease to some degree.