心肌肌钙蛋白Ⅰ床边定性测定对急性心肌梗死的快速诊断

Qualitative Analysis of Cardiac Troponin I in Bed Side for Rapid Diagnosis of Acute Myocardial Infarction

为了观察急性心肌梗塞 (AMI)患者血中心肌肌钙蛋白Ⅰ (cTnⅠ )的动态变化 ,采用一步法免疫色谱干膜层析活性卡 ,快速检测了 2 0例AMI患者的cTnⅠ并与CK -MB作对照。结果发现cTnⅠ和CK -MB的阳性率分别为 90 %、60 % ,两者之间有显著差异 ;两者特异性分别为 92 .9%、85 .7% ,无统计学显著差异 ;心脏病患者CK -MB也有升高 ,而cTnⅠ阴性。结论 :cTnⅠ活性卡操作简便 ,灵敏性高 ,可用于床边检测。

To observe the dynamic variations of cardiac troponin I (cTnⅠ) in patients with acute myocardial infarction(AMI), cTnⅠ was rapidly tested in 20 patients with AMI using one-step immune chromatographic biocard and compared with CK-MB. The positive rates of cTnⅠ and CK-MB were 90% and 60% respectively. There was a significant difference between cTnⅠ and CK-MB. Their specificities were 92.9% and 85.7% respectively. There was no statistic difference. CK-MB had elevated in non-AMI cardiac patients but cTnⅠ was not detected. In conclusions, troponin biocard is easy to operate and sensitive for detection of cTnⅠ, and may be used in bed side testing.