纤维支气管镜下局部灌注抗痨药物凝胶治疗支气管内膜结核

TREATMENT FOR ENDOBRONCHIAL TUBERCULOSIS BY PARTIALLY POURING ANTITUBERCULOTIC GLUEY DRUGS THROUGH FIBEROPTIC BRONCHOSCOPE

目的 :探索支气管内膜结核治疗新途径。方法 :经纤维支气管镜将抗痨药物凝胶灌注于病变支气管黏膜。结果 :该方法可以促进炎症吸收 ;软化、稀释局部干酪坏死物质 ,使之易于排出 ,直至完全消失 ;缩小浸润增殖型病灶 ,乃至完全消失。结论 :适时局部灌注抗痨药物凝胶治疗支气管内膜结核 ,可以提高治愈率 ,减少并发症 ,保护肺功能 ,使部分患者免于外科手术。该方法还可以使痰菌迅速转阴 ,减少传染源 。

Objective To explore a new way of treatment for endobronchial tuberculosis. Methods To pour antituberculotic gluey drugs through fiberoptic bronchoscope to the endotracheal mucosa suffering from tuberculosis. Results This way may promote the absorption of inflammation, soften and dilute focal substances of caseous necrosis, to make them be eliminated easily till these substances disappear completely; and may diminish the focus of the hyperplasia till they fade away. Conclusions The treatment for endobronchial tuberculosis by partially pouring antituberculotic gluey drugs may raise the curative rate, reduce the complications, protect pulmonary function and keep some patients from operation. Through this method, the tubercle bacilli in sputum may become negative promptly. So the treatment also plays a direct role in controlling the epidemic of tuberculosis by reducing the infectious sources.