血管内超声多普勒技术对Budd-Chiari综合征介入治疗前后压力与血流速度变化的关系研究

Study of Relationship between Blood Flow Velocity and Pressure of Budd-Chiari Syndrome with Intravascular Ultrasound Doppler Flow Mapping

目的 研究Budd Chiari综合征 (BCS)患者介入治疗 (PTA)前后的压力与平均峰值速度 (APV )的变化关系。方法 使用血管内多普勒导丝测定 2 7例BCS患者PTA前后的下腔静脉和 /或肝静脉 (IVC/HV )的血流速度 ,同时测定压力。结果 PTA前 ,在狭窄和闭塞病变 ,压力和APV呈负相关 (狭窄 :IVC :r =-0 .82 ,P <0 .0 0 1;HV :r =-0 .83 ,P <0 .0 0 1。闭塞 :IVC :r =-0 .45 ,P <0 .0 5 ;HV :r =-0 .44 ,P <0 .0 5 )。PTA后 ,无这种相关关系。结论 PTA前 ,在狭窄和闭塞血管 ,其狭窄远心端的压力与血流速度呈不同程度的负相关关系 ;而PTA后 ,这种相关关系消失。

Objective To investigate the relationship between inferior vena cava/hepatic vein (IVC/HV) stenosis/occlusion pressure and average peak velocity (APV). Methods With Doppler guidewire, APV of 27 BCS patients were measured in IVC/HV before and after PTA. At the same time, the pressure of the same position was measured. Results Before PTA, in stenotic and occlusion vessels, pressure was negatively related to APV (Stenosis: IVC: r =-0.82, P <0.001;HV: r =-0.83, P <0.001. Occlusion: IVC: r =-0.45, P <0.05;HV: r =-0.44, P <0.05). After PTA, this correlativity was no longer existence. Conclusion Before PTA, in stenotic and in occlusion vessel, the pressure were negatively related to APV in different degrees. After PTA, this correlativity was no longer existence. Consequently, simple measurement of pressure couldn't completely take the place of APV.