犀羚合剂治疗急性高血压脑出血风痰上扰证的临床研究

Clinical study on Xiling mixture(犀羚合剂) in treatment of acute hypertensive cerebral hemorrhage with upstirring of windphlegm syndrome(风痰上扰证)

目的 :观察犀羚合剂治疗急性高血压脑出血风痰上扰证的临床疗效。方法 :将 5 5例急性高血压脑出血风痰上扰证患者随机分为治疗组 (犀羚合剂 +常规治疗 )和单纯西医治疗对照组 ,观察 2组治疗前后综合疗效、神经功能、血肿量、中医证候积分、血液流变学等指标变化。结果 :治疗组总有效率 (96 .4 % )显著优于对照组(88.9% ,P<0 .0 5 )。在恢复神经功能、提高生活质量、促进血肿吸收、降低中医证候积分、改善血液流变性等方面 ,治疗组明显优于对照组 (P<0 .0 1或 P<0 .0 5 )。结论 :犀羚合剂治疗急性高血压脑出血风痰上扰证 ,能降低血液黏度 ,改善微循环 ,促进神经功能恢复 。

Objective:To observe the clinical effect of Xiling mixture(犀羚合剂) in treatment of acute hypertensive cerebral hemorrhage(HCH) with upstirring of windphlegm syndrome(风痰上扰证).Methods:Fiftyfive cases with acute HCH with upstirring of windphlegm syndrome were randomly divided into 2 groups: the treatment group (Xiling mixture plus routine treatment)and the control group (routine treatment).The changes of the therapeutic effects,neurological function,the hematoma volume,traditional Chinese medicine(TCM) syndrome score and the hemorrheology were observed.Results:The total effective rate of the treatment group was 96.4%.It is significantly higher than that of the control group(88.9%, P <0.05 ).The neurological function recovery,the quality of life,the hematoma absorption,the TCM syndrome score and the hemorrheology parameters in the treatment group were significantly improved than those of the control group( P <0.01 or P <0.05).Conclusions:Xiling mixture is effective in treating acute HCH with upstirring of windphlegm syndrome.It can lower blood viscosity,improve microcirculation,promote neurological recovery and improve the quality of life as well.