黄芪注射液与刺五加注射液合用治疗急性病毒性心肌炎疗效观察

Observation on therapeutic effect of astragulas injection combined with acanthopanax senticosus injection for acute viral myocarditis

目的 :观察黄芪注射液合用刺五加注射液治疗急性病毒性心肌炎的临床疗效 ,并探讨其作用机制。方法 :将 131例急性病毒性心肌炎患者随机分为 2组 :治疗组 6 8例 ,给予黄芪注射液与刺五加注射液静滴 ;对照组 6 3例 ,给予促进心肌细胞代谢药物与极化液静滴。结果 :治疗组治愈率 5 8.0 6 % ,总有效率 93.5 5 % ,均显著高于对照组 (分别为 2 9.4 1%和 6 8.6 3% ) ,P<0 .0 5和 P<0 .0 1。治疗组的临床症状缓解、心肌酶谱改善、心电图 ST T改变、各种传导阻滞和窦性心律失常等恢复均明显优于对照组 (P<0 .0 5或 P<0 .0 1) ,对心功能的改善 ,2组间无显著性差异 (P>0 .0 5 )。未见任何不良反应。结论 :黄芪注射液与刺五加注射液合用治疗急性病毒性心肌炎是一种安全有效的方法。

Objective:To observe the clinical curative effects of astragulas injection combined with acanthopanax senticosus injection for acute viral myocarditis (AVM),and to investigate its mechanism.Methods:One hundred and thirtyone cases with AVM were randomly divided into 2 groups.Sixtyeight cases in treatment group was treated with astragulas injection combined with acanthopanax senticosus injection infused intravenously .Sixtythree cases in control group was treated with facilitating myocardial cells′ metabolic drug and glucoseinsulinpotassium(GIK) infused intravenously.Results:The recovery rate and total effective rate in treatment group (58 06% and 93 55%) were higher than those in control group(29 41% and 68 63%, P <0 05 and P <0 01).The efficacy of treatment group was obviously improved than that of control group in relieving the clinical symptoms ( P <0 01),ameliorating the myocardial enzyme ( P <0 05),recovering electrocardiogram STT changs ( P <0 01),various block ( P <0 01)and sinus arrythmia( P <0 05) etc.The curative effects on improving the heart function showed no significant between the 2 groups ( P >0 05).No sideeffects were observed.Conclusions:It′s safe and effective to treat AVM with astragulas injection combined with acanthopanax senticosus injection.