以杯[4]芳烃衍生物为载体的钾离子选择电极的研究

Studies of potassium ion-selective electrode based on calix [4] arene derivatives

目的:研制新的以杯[４]芳烃衍生物为载体的PVC膜钾离子选择电极。方法:以3种杯[４]芳烃衍生物为载体,癸二酸二辛酯或邻苯二甲酸二辛酯为增塑剂．四(4－氯)苯硼钾为离子定域体制得了PVC膜钾离子选择电极,测试了该类电极对钾离子的响应性能和对7种阳离子的选择性系数。结果:以5,11,17,23－四叔丁基－25,26,27,28－四[２－(乙氧基碳基)苄氧基]杯[４]芳烃为载体所制得的电极(电极I)对钾离子有良好的能斯特响应,该电极的选择性系数优于电极Ⅱ和Ⅲ。分别用电极I,Ⅱ,Ⅲ对青霉素V钾中的钾含量进行了测定,其结果均与原子吸收法基本一致。结论:所制得的上述电极是一类新的钾离子选择电极,有实用价值。

Aim: To develop a novel PVC membrane potassium ion-selective electrode based on calix [4] arene derivatives. Methods: The potassium ion-selective electrode was prepared by using calix[4] arene derivatives as carriers, dioctyl sebacate(DOS) or dioctyl phthalate(DOP) as plasticizer, and potassium tetrakis(4-chloropheny) borate as ionic additive. The response characteristics of K+ and the selectivity coefficients logKK+pot, M of the electrodes were estimated. Results: The electrode based on 5, 11, 17,23-tetra-tert-butyl-25,26,27,28-tetrakis[o-(ethoxycarbonyl)benzyloxyl]calix[4]arene(electrode Ⅰ ) exhibited almost Nerstian response characteristics towards K+ and its selectivity coefficients were preferable to those of electrodes Ⅱ and Ⅲ . The content of K+ in Penicillin-V had been determined by potassium ion-selective electrodes Ⅰ , Ⅱ and Ⅲ, respectively, all of which were consistent with that of atomic absorption spectrometric analysis. Conclusion: The electrode based on calix [ 4 ] arene derivatives is a novel potassium ion-selective electrode which may be used in practice.