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NOD小鼠口服胰岛素诱导免疫耐受机制探讨 被引量:2

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出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2002年第1期67-68,共2页 Chinese Journal of Endocrinology and Metabolism
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参考文献3

  • 1Bergerot I,Corinne P,Jacob P,et al.A cholera toxoid insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes[].Proceedings of the National Academy of Sciences of the United States of America.1997
  • 2Madaniel ML,Kwon G,Hill JR,et al.Cytokines and nitric oxide in islet inflammation and diabetes[].Proceedings of the Society for Experimental Biology and Medicine.1996
  • 3Rabinovitch A,Suarez-Pinzon WL.Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus[].Biochemical Pharmacology.1998

同被引文献27

  • 1Rabinovitch A.Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM[J].Diabetes,1994,43 (5):613-621.
  • 2O'Brien BA,Harmon BV,Cameron DP,et al.Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse[J].Diabetes,1997,46(5):750-757.
  • 3Wegmann DR,Eisenbarth GS.It's insulin[J].J Autoimmun,2000,15(3):286-291.
  • 4Mathis D,Vence L,Benoist C.Beta-Cell death during progression to diabetes[J].Nature,2001,414 (6865):792-798.
  • 5Pozzilli P.The DPT-1 trial:a negative result with lessons for future type 1 diabetes prevention[J].Diabetes Metab Res Rev,2002,18(4):257-259.
  • 6Muir A,Peck A,Clare-Salzler M,et al.Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription[J].J Clin Invest,1995,95(2):628-634.
  • 7Gotoh M,Maki T,Kiyoizumi T,et al.An improved method for isolation of mouse pancreatic islets[J].Transplantation,1985,40(4):437-438.
  • 8Fox CJ,Danska JS.IL-4 expression at the onset of islet inflammation predicts nondestructive insulitis in nonobese diabetic mice[J].J Immunol,1997,158(5):2414-2424.
  • 9Liu D,Pavlovic D,Chen MC,et al.Cytokines induce apoptosis in β-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-)[J].Diabetes,2000,49(5):1116-1122.
  • 10Hartmann B,Bellmann K,Ghiea I,et al.Oral insulin for diabetes prevention in NOD mice:potentiation by enhancing Th2 cytokine expression in the gut through bacterial adjuvant[J].Diabetologia,1997,40 (8):902-909.

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