期刊文献+

骨肉瘤病人雌孕激素受体表达与临床及预后的关系

CLINICAL SIGNIFICANCE OF ESTROGEN RECEPTOR (ER) AND PROGESTERONE RECEPTOR (PR) IN OSTEOSARCOMA
下载PDF
导出
摘要 ①目的 探讨骨肉瘤病人雌激素受体 (ER)、孕激素受体 (PR)的表达与其临床表现及预后的关系。②方法 结合临床资料及随访结果对 6 5例骨肉瘤病人ER ,PR表达情况进行回顾性分析。③结果 不同性别、年龄、发病部位的骨肉瘤病人ER ,PR表达的阳性率无显著性差异 (χ2 =0 .5 92~ 2 .2 4 2 ,P >0 .0 5 )。临床无转移、存活时间长的骨肉瘤病人ER ,PR表达的阳性率高于临床有转移、存活时间短者 ,差异有显著性 (χ2 =4 .0 7~ 11.85 ,P <0 .0 5 )。④结论 骨肉瘤病人ER ,PR阳性率检测可为骨肉瘤生物学行为。 Objective\ To investigate the relationship between ER,PR expression and clinical characteristics as well as prognosis of osteosarcoma.\ Methods\ The clinical materials and follow up results of 65 cases of osteosarcoma were evaluated retrospectively for the expression of ER and PR in osteosarcoma. \ Results\ There were no significant differences of ER, PR expression among different sex, ages and tumor sites( χ 2=0.592-2.242,P >0.05). The positive rates of expression of ER and PR in the sections from osteosarcoma with no metastasis, and the patients with longer survival time were higher than those in the tumor with opposite conditions. The differences had statistical significance ( χ 2=4.07-11.85,P <0.05).\ Conclusion\ The detection of expression of ER and PR may provide rationale for biological behavior and hormonal therapy of osteosarcoma and prognostic assessment of the patients.
出处 《青岛大学医学院学报》 CAS 2002年第1期64-65,共2页 Acta Academiae Medicinae Qingdao Universitatis
关键词 骨肉瘤 雌激素受体 孕激素受体 预后 osteosarcoma receptors, estrogen receptors, progesterone prognosis
  • 相关文献

参考文献7

  • 1Gupta PK. Cytodiagnostic patterns of metaplastic breast carcinoma in aspiration samples: a study of 14 cases [J]. Diagn Cytopathol, 1999,20:10
  • 2Chung LW, Kao C, Sikes RA, et al. Human prostate cancer progression models and therapeutic intervention[J]. Hinyokika Kiyo, 1997,43:815
  • 3Henderson BE, Feigelson HS. Hormonal carcinogenesis[J]. Carcinogenesis, 2000,21:427
  • 4刘金钊,乐兴祥,李玉军.骨肉瘤雌、孕激素受体的病理学研究[J].中华外科杂志,1998,36(4):245-246. 被引量:3
  • 5Stedman KE. Estrogen receptor proteins in diverse human tumors[J]. Arch Surg, 1980,115:244
  • 6河野秀树. 实验骨肉肿におけるエストロゲンおふびエストロゲンレセブタへ研究[J]. 日整会志,1991,65:207
  • 7韩守威.人体正常骨及骨恶性肿瘤组织雌激素及孕激素受体分析[J].中国病理生理杂志,1993,9:97-98.

二级参考文献4

  • 1唐建林,中华病理学杂志,1994年,23卷,120页
  • 2王保太,临床与实验病理学杂志,1992年,8期,165页
  • 3刘子君,骨关节病理学,1992年,142页
  • 4许良中,肿瘤,1984年,4期,18页

共引文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部