蚊帐防疟作用的Logistic分析

Logistic analysis of the role of the bednet in malaria prevention

目的 评价元江流域地区蚊帐的防疟作用。方法 对 1756名对象进行横断面调查,采用无条件逐步lo-gistic回归分析所得资料。结果 经单因素分析,在所调查的15个变量中,7个与间接荧光抗体实验（IFAT）阳性明显或极可能有统计学联系;逐步logistic多元回归分析结果为,使用蚊帐和年龄小于15岁的调整后比值比（OR）分别是0.578（95％CI:0.467～0.716）和0.418（95％CI:0.33～0.525）,这显示与预防疟疾感染有显著联系,但此二因素不存在统计学上的相互作用。结论 在这一地区,使用蚊帐对于防止疟疾感染有意义深远的作用;山区半山区下坝生产在田棚过夜人群的调整后OR值为0.328（95％CI:0.199～0.540）,这说明作用更明显;但这一保护作用受蚊帐覆盖率,媒介生物学特性和人类行为的影响。

ve To assess the role of bednet in malaria prevention in Yuanjiang River Valley Area. Methods A cross - sectional investgation was conducted in which a total of 1 756 subjects were studied. The data were analysed with unconditional stepwise logistic regression. Results Among 15 variables investigated, 7 ones were tested by univariate analysis as statistical obviously or borderline significant association with IFAT posi-tivity. As a result of stepwise multivariate logistic regression, adjusted odds ratios (OR) of bednet use and < 15years old were respectively 0.578(95%CI:0.467 - 0.716) and 0.418(95%CI:0.333 - 0.525), significantly associated with the protection of malaria infection, however, no statistical interaction between them. Conclusion In the region, the use of bednets can result in significant protection from malaria infection, especially among people staying outdoors for the night with adjusted OR 0.328(95%CI:0.199 - 0.540)in field shacks of foothill from half-hill . However the protective role is affected by bednet coverage, vector biology characteristics and human behaviors.