云南省中缅边境地区疟疾血清流行病学调查分析

Sero - epidemiological investigation of malaria prevelence in China - Mynamar border area of Yunnan Province

目的 了解中缅边境一线县、二线县、及一线三个县的一线自然村、二线自然村的疟疾流行情况,为制定边境地区疟疾防治措施提供科学依据。方法 采用IFAT对中缅边境沧源、耿马及孟连一线县与双江县、永德县二线县,边境线3县一线自然村和二线自然村进行疟血清流行病学调查,用电脑软件EPI6X2检验法进行数据分析。结果一线县抗体阳性率23.88％（568/2379）,二线县抗体阳性率1.40％（10/712）,一线县显著高于二线县（x2=180.54;P<0.01）。一线县的一线自然村抗体阳性率33.05％（467/1413）,二线自然村抗体阳性率10.46％（101/966）,一线自然村显著高于二线自然村（x2=159.92;P<0.01）。结论IFAT抗体阳性率和阳性GMRT说明靠近边境地带比远离边境的地带疟疾流行更为严重。应加强出入境人员的防治工作,才能控制边境疟病流行。

ve To understand malaria prevalent status along China - Mynamar bordet area and provide scientific basis for making malaria control strategies. Methods The three counties of Cangliang,Geng-ma and Menglian bordering with Mynamar were taken as the first - line counties and the counties of Shuangjiang, Yongde not bordering with Mynamar were taken as the second - line counties, while the villages bordering and not bordering with Mynamar in the three firat - line counties were taken as the first - line and second - line villages. Seroepidemioligy was conducted using IFAT in the above mentioned counties and villages for investigating malaria prevalent situation and the data were statistically analyzed by using EPI6 software. Results The antibody positive rates in the first-line and second-line counties were 23. 88% (467/1413)and 1.40% (10/712), significantly higher in the former than in the latter( x2=180. 54, P < 0. 01). While the antibody positive rates in the first- line and second- line villages of the first- line counties were 33.05%(467 - 1413), and 10.46%(101/ 966)also significantly higher in the first- line villages than that in the second- line villages(x2 = 159.92, P < 0.01). Conclusion The results show that malaria is much seriously prevalent in bordering areas than that non -bordering areas. To control the prevalence of malaria effective measures be taken to strengthen the examination of the population entering and leaving the bordering areas.