肺癌患者红细胞天然免疫功能研究

The study of nature immune function of erythrocytes in patients with lung cancer

目的 探讨肺癌患者红细胞天然免疫粘附 (ENIA)功能。方法 采用红细胞快速天然免疫粘附 S1 80肿瘤细胞实验方法 ,对 35例肺癌患者进行研究。结果 肺癌患者 ENIA功能显著低于正常对照组 (P<0 .0 1) , 、 期肺癌患者 ENIA显著低于 、 期患者 (P<0 .0 5 )。结论 肺癌患者 ENIA功能显著低下 ,并随着病情的进展进一步降低。 ENIA功能试验可作为肺癌患者临床免疫的测定指标 ,对肺癌的发生。

Objective To investigate the nature immune adherence function of erythrocytes (ENIA) in patients with lung cancer.Methods The test of nature immune adherence of erythrocytes to S 180 tumor cells was used in 35 cases of lung cancer.Results The nature immune adherence of erythrocytes in lung cancer group showed obviously lower than that in healthy control group( P <0.01),the nature immune adherence of erythrocytes in lung cancer stage Ⅲ and Ⅳ group was significantly lower than that in lung cancer (stage Ⅰ and Ⅱ)group( P <0.05).Conclusion The nature immune adherence of erythrocytes in cases of lung cancer was obviously lower and gradually dropped with the progress of lung cancer.So the test of nature immune adherence of erythrocytes may be an indicator for evalation of patients' clinical immune state,which may reflect the development and the prognosis of lung cancer.