CT或MRI引导立体定向活检方法的研究

The Study of CT or MRI - guided Stereotactic Biopsy for Brain Deep Lesions

目的 探讨用CT或MRI引导立体定向对脑深部病变进行活检手术的可行性和准确性。方法 用CT或MRI引导的脑立体定向手术对605例脑深部病变进行活检以期获得病变的组织学诊断。其中男357例,女248例。年龄:2.5～78岁,平均37.7岁。用CT引导立体定向活检515例,用MRI引导的定向活检90例。结果 522例(86.28％)获得脑肿瘤的病理组织,39例(6.44％)为炎性病理组织,其他病理组织23例(2.4％),16例(2.65％)未能提供病理学诊断,阳性诊断率97.35％,并发症发生13例(2.47％),死亡2例,死亡率为0.33％。结论 采用CT或MRI引导的立体定向脑深部病变活检是一种诊断准确率高,安全可靠,并发症少,创伤轻微,死亡率极低的手术方法,值得推广应用。

Objective The study of histological diagnostic efficacy and accuracy by CT or MRI - guided stereotactic biopsy for the brain deep lesions. Methods CT or MRI - guided stertotactic biopsies were performed in 605 cases with intracranial deep lesions. The CT- guided stereotactic biopsy in 515 cases,MRI -guided stereotactic biopsy in 90 cases. Results Brain tumors were diagnosed pathologically in 522(86.28%) cases,inflammatory response in 39(6.44%) cases, abnormal but nonspecific lesions in 23(2.4%) cases,and 16(2.65%) were nondiagnostic. The total positive rate of biopsy was 97.35%. Complications associated with biopsy occurred in 13 patients(2.47% ) and 2(0.33% ) died following the procedure.Conclusions The CT or MRI - guided stereotactic biopsy was represented a safe and reliable m ethod for histological diagnosis of many intracranial deep lesions.