QT离散度与冠心病严重程度的相关性研究

The possible relationships between QT dispersion and serious extent of coronary heart disease

目的探讨QT离散度 (QTd)与冠脉狭窄程度及冠心病心功能的关系。方法测量 4 35例 (男 30 8例 ,女 12 7例 ,平均年龄 5 7 1± 5 2岁 )冠状动脉造影者的体表心电图QTd。结果冠状动脉狭窄组QTd较冠脉正常组明显延长 (P <0 0 0 1)。在狭窄程度大于或等于 75 %组和狭窄小于 75 %组间 ,QTd差异有显著意义 (P <0 0 0 1) ,单支病变和多支病变的QTd差异无统计学意义 (P >0 0 5 ) ,而左室射血分数 (LVEF) >4 0 %和LVEF≤ 4 0 %两组间 ,QTd差异有非常显著意义 (P <0 0 0 1)。结论QTd与冠脉狭窄程度及左室射血功能有关。

Objective To study the possible relationships between QT dispersion and serious extent of coronary heart disease Methods QTd and QTcd among 435 (308 male, 127 female, mean age 57.1±5.2 years) patients receiving coronary angiography were studied. The relationships between QTd and single vessel lesion, multiple vessel lesion and LVEF were also discussed. Results The results showed that the QTd of patients with coronary artery stenosis and patients with normal coronary artery were significant difference ( P <0.001). The QTd was also different between the patients with coronary artery stenosis (≥75%) and the patients with coronary artery stenosis (<75%, P <0.001). The QTd is positively correlated with coronary stenosis degree. The QTd of single vessel lesion and multiple vessel lesions showed no significant difference ( P >0.05). The QTd of patients with LVEF≤40% and patients with LVEF≤40% showed significant difference ( P <0.001). Conclusion The results suggest that QTd is related to the degree of coronary stenosis and left ventricular function.