β_2-糖蛋白I基因多态性研究的新进展
被引量:1
摘要
β2-糖蛋白I(β2-GPI)是血浆载脂蛋白的组分之一,它参与血脂代谢,作用于凝血机制,具有结合磷脂(PL)的功能,是抗磷脂抗体(APA)与PL结合必需的辅助因子。β2-GPI基因呈多态性,在普通人群存在几个等位基因,遗传决定的变异影响β2-GPI与PL的结合,从而影响APA的产生。本文就其基因多态性研究进展进行综述。
出处
《国外医学(神经病学.神经外科学分册)》
2002年第2期103-106,共4页
Foreign Medical Sciences(Section On Neurology & Neurosurgery)
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