双水平气道正压无创通气对呼吸衰竭病人血气指标的影响

Effects of non-invasive bi-level positive airway pressure ventilation on COPD patients with type Ⅱ respiratory failure.

目的 探讨双水平气道正压无创通气 (Bi PAP)对慢性阻塞性肺疾病 (COPD)并 型呼吸衰竭的治疗价值。方法 病情相似的 89例 COPD病人分为三组 :对照组 ,Bi PAP组和气管插管组 ;分别予相应治疗措施治疗 3天后比较三组病人在治疗前后的血气分析指标。结果 治疗前三组病人血气分析指标 (Pa O2 、Pa CO2 、p H)差异无显著性 (P>0 .0 5 )。治疗后 Bi PAP组和气管插管组与治疗前比较明显改善 (P<0 .0 5 )。与对照组比较也明显改善 (P<0 .0 5 )。插管组血气改善优于 Bi PAP组 (P<0 .0 5 )。结论 双水平气道正压无创通气可有效治疗 COPD并

Objective To examine the effect of non invasive bi level positive airway pressure (BiPAP)ventilation in COPD patients with type Ⅱ respiratory failure(RF).Methods 89 cases of COPD patients with RF patients were divided into three groups:control group,BiPAP group and intubation group.Arterial blood gas analyses were performed before and after 3 days treatment and the comparison of results were made among the three groups.Results There were no significant differences of PaO 2,PaCO 2 and pH among three groups before treatment.After treatment,the blood gas analysis showed that three of blood gas indices(PaO 2,PaCO 2,pH)were greatly improved in BiPAP group and intubation group( P <0.05).The improvement was greater in intubation group than BiPAP group.Conclusion The non invasive BiPAP ventilation could improve the blood gas indices in COPD patients with RF.