三黄泻心汤传统饮片汤剂与中药配方颗粒汤剂中生物碱的定性鉴别

Identification of Alkaloids between Sanhuang Decoction for Purging Stomach-fire and Its Concentrated Granule

目的:探讨中药配方颗粒汤剂代替传统饮片汤剂的可能性。方法:对比研究了三黄泻心汤传统饮片汤剂与中药配方颗粒汤剂中生物碱类的薄层色谱(TLC)、高效液相色谱(HPLC)。结果:三黄泻心汤传统饮片汤剂与中药配方颗粒汤剂中生物碱类TLC、HPLC色谱图大致相似,但色谱图显示中药配方颗粒汤剂中生物碱类成分含量高。结论:三黄泻心汤的中药配方颗粒汤剂具研究、开发意义。

Objective: Study is to discuss the feasibility that a traditional decoction is substitued by its concentrated granule. Method: A contrastive research was used to analyze alkaloids in Sanhuang decoction for purging stomach-fire and its concentrated granule by TLC and HPLC methods. Result: The experimental results indicate the alkaloids in Sanhuang decoction for purging stomach-fire and its concentrated granule are similar,but the content of alkaloids in concentrated granule is higher. Conclusion: The research and exploitation of classical prescription concentrated granule has great significance.