1—(3—吡啶甲酰)—4—芳基氨基硫脲类和3—(3—吡啶基)—4—芳基—1,2,4—三唑啉—5—硫酮类化合物^(13)C—NMR谱研究

STUDIES ON CARBON-13 NUCLEAR MAGNETIC ROSONANCE SPECTRA OF 1-NICOTINYL-4-ARYLTHIOSEMICARBAZIDES AND 3-(3-PYRIDYL) -4-ARYL-l, 2, 4-TRIAZOLINE-5-THIONES

本文测定了1-(3—吡啶甲酰)—4—苯基氨基硫脲、3—(3—吡啶基)—4—苯基—1,2,4—三唑啉—5—硫酮等8个新化合物的^(13)C NMR谱,运用质子宽带去偶、偏共振去偶,结合信号强度对比、苯基取代基效应的计算,同时与模型化合物对照,一一归属了其谱峰。本文对这两类化合物之间的^(13)C NMR谱差异进行了探讨,并得到了在吡啶环3位取代的甲酰肼基对吡啶环各碳取代基效应的数据。

The carbon -13 nuclear magnetic resonance spectra of eight new compounds including 1 -nicotinyl-4-phenylthiosemicarbazide and 3-(3-pyridyl)-4-phcnyl -1, 2, 4-triazoline-5-thione were recorded. The chemical shifts of various carbon resonances have been assigned on the basis of the application of proton broad band decoupling and off resonance decoupling techniques, the comparison of signal intensity, the calculation based on substituent effect, and comparison with the chemical shifts of the model compounds. The difference between thiosemicarbazides and t, 2, 4-triazoline-5 - thiones in 13C NMR was discussed. In addition, the data of the effect of substituent of hydrazide on the C-13 chemical shifts in 3-monosubstituted pyridines were obtained.