阿斯匹林-潘生丁对脑血栓患者血小板聚集性的影响

The effect of aspirin and persantin on the platelet aggregation in patients with cerebral thrombosis

本文报道了25例脑血栓形成患者用阿斯匹林—潘生丁治疗前后的循环血小板聚集率和血小板电泳时间的测定结果。并与正常人进行了比较。结果表明:患者在治疗前和正常人相比此二项指标具有明显差异(P<0.01),治疗后向正常转化,临床症状亦好转。提示阿斯匹林—潘生丁能通过提高血小板表面电荷,抑制血小板聚集,改善微循环,起到治疗作用。

The article reports the results of measuring the circulating platelet aggregate ra-te, and the platelet electrophoretic time in 25 patients with cerebral thrombosis tre-ated with aspirin and persantin 25 normal subjects were taken as control. The re-sults showed that before treatment, the two indexes of the patients were signifi-cantly different from those of the control, whereas after treatment, the two indexesand clinical conditions improved simultaneuosly. It was suggested that increasingthe surface charge of platelets, depressing the aggregation of pltelets and improvingthe microcriculation be important effects of the drugs on the patients.