摘要
目的:对中药引起的过敏反应进行统计分析。方法:收集1999~2001年间国内主要医药期刊报道的中药过敏反应187例,从性别、年龄、发生时间、用药途径、临床表现加以分析,并统计出较易发生过敏反应的前5位药物。结果:中药过敏反应的发生与性别、年龄无关,与用药途径有关,注射用药较易引发过敏反应(109例)。过敏反应发生时间最短为用药后3min,最长为停药后7d,多数发生在用药过程中(167例)。主要表现为皮肤反应(122例),其次为过敏性休克(26例),过敏性鼻炎 (7例),过敏性哮喘(6例),过敏性紫瘢(5例),药物热(17例)等。结论:中药不良反应中以过敏反应最为常见,应引起注意并及时预防。
Objective: To analyze allergic reactions caused by traditional Chinese medicines statistically. Method: 187 ADRs were collected from national medical journals of 1999-2001 in consideration of gender, age, time, route and clinical manifastations. Results: ADR of traditional Chinese medicines was in no relation with gender and age of patients. But it was connected with route of administration. Drugs for injection ranked first on the ADR list, accounting for 109 cases. The time of ADR occurence ranged from three minutes to seven days when drugs being taken, mostly in the period of treatment. Main manifestations of ADR were as follows: dermoreaction (122 cases), allergic shock (26), allergic rhinitis (7), allergic asthma (6), anaphylactoid purpura (5) and drug fever (17). Conclusion: Allergic reaction is the most common ADR and should be given close attention and prevented timely.
出处
《药物不良反应杂志》
2002年第2期81-83,共3页
Adverse Drug Reactions Journal
关键词
中药
过敏反应
合理用药
统计分析
Traditional Chinese medicines
allergic reactions