期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

牛磺酸转运体 被引量：2

Taurine transporter (TAUT)
下载PDF
导出
摘要 牛磺酸是机体内含量最丰富的自由氨基酸 ,具有十分广泛的生物学效应。牛磺酸多集中于可兴奋组织中 ,且大部分分布在细胞内 ,这是牛磺酸通过细胞膜上牛磺酸转运体 (TAUT)转运至细胞内所致。TAUT有多种类型 ,各型分布不同 。
作者 石彦荣 唐朝枢
机构地区 北京大学第一医院心血管病研究所
出处 《生理科学进展》 CAS CSCD 北大核心 2002年第2期145-147,共3页 Progress in Physiological Sciences
关键词 牛磺酸 牛磺酸转运体 克隆 TAUT
分类号 Q517 [生物学—生物化学] Q591.2 [生物学—生物化学]
  • 相关文献

参考文献9

  • 1[1]Huxtable RJ. Physiological action of taurine. Physiol Rev, 1992, 72:101～146.
  • 2[2]Sammanda R, Frederick HL, Virendra BM, et al. Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta. Biochem J, 1994, 300:893～900.
  • 3[3]Stevens MJ, Hosaka Y, Masterson JA, et al. Downregulation of the human taurine transporter by glucose in cultured retinal pigment epithelial cells. Am J Physiol, 1999, 277:E760～771.
  • 4[4]Han X, Burdrean AM, Chesney RW. Molecular cloning and functional expression of an LLK-pK1 cell taurine transporter that is adaptively regulated by taurine. Adv Exp Med Biol, 1998, 442:261～268.
  • 5[5]Han X, Budreau AM, Chesney RW. Ser-322 is a critical site for PKC regulation of the MDCK cell taurine transporter (pNCT). J Am Soc Nephrol, 1999, 10:1874～1879.
  • 6[6]Takeuchi K, Toyohara H, Sakaguchi M. A hyperosmotic stress-induced mRNA of carp cell encodes Na(+)- and Cl(-)-dependent high affinity taurine transporter. Biochim Biophys Acta, 2000, 1464:219～230.
  • 7[7]Qian X, Vinnakota S, Edwards C, et al. Molecular characterization of taurine transport in bovine aortic endothelial cells. Biochim Biophys Acta, 2000, 1509:324～334.
  • 8[8]Busui RP, Sullivan KA, Huysen CV, et al. Depletion of taurine in experimental diabetic neuropathy: implications for nerve metabolic, vascular, and functional deficits. Exp Neurol, 2001, 168:259～272.
  • 9[9]Bitoun M, Levillain O, Tappaz M. Gene expression of the taurine transporter and taurine biosynthetic enzymes in rat kidney after antidiuresis and salt loading. Arch Eur J Physiol, 2001, 442:87～95.

同被引文献49

  • 1尹时华.L-精氨酸对肾性高血压心肌肥厚大鼠主动脉血管平滑肌HSP^(70)表达的影响[J].中国心血管杂志,1999,4(3):191-192. 被引量：10
  • 2Yamazaki T, Yazaki Y. Molecular basis of cardiac hypertrophy[J]. Z Kardiol, 2000,89(1):1.
  • 3Shimoyama M, Hayashi D, Takimoto E, et al. Calcineurin plays a critical role in pressure overload-induced cardiac hypertrophy[J]. Circulation, 1999,100(24) :2449.
  • 4Mukherjee D, Sen S.Alteration of cardial collagen phenotyes in hypertensive hypertrophy: role of blood pressure[J] .J Mol Cell Cardiol,1993,25(2) :185.
  • 5Schieffer B, Paxton WG, Marrero MB, et al .Importance of tyrosine phosphorylation inangiotensin type 1 receptor signaling[ J]. Hypertension,1996,27(3 Pt2) :476.
  • 6Aoki H,Richmond M,Izumo S, et al. Specific role of the extracellular signal-regulated kinase pathway in angiotensin Ⅱ-induced cardiac hypertrophy in vitro[J]. Biochem J,2000,347(Pt1):275.
  • 7Sadoshima J, Izumo S. Molecular characterization of angiotensin Ⅱ -induced hypertrophy of cardiac myocytes and hyperplasis of cardiac fibroblasts[ J]. Circ Res, 1993,73(3) :413.
  • 8Weber KT,Sun Y,Campbell SE, et al. Chronic mineralocorticoid excess and cardiovascular remodeling[ J]. Steroids, 1995,60(1): 125.
  • 9ROIG-PEREZ S,FERRER C,RAFECAS M,et al.Correlation of taurine transport with membrane lipid composition and peroxidation in DHA-enriched Caco-2 cells[J].Journal of Membrane Biology,2009,228:141-150.
  • 10ITO T,OISHI S,TAKAI M,et al.Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice[J].Journal of Biomedical Science,2010,17(Suppl.1):S20.

引证文献2

二级引证文献12

生理科学进展
2002年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部