80例多器官功能衰竭病人血清甲状腺激素的变化

The changes of serum thyroid hormone in 80 cases of multiple organ failure

总结80例多器官功能衰竭病人血清T_3、T_4及其中58例血清rT_3的变化。结果表明:多器官功能衰竭病人血清T_3、T_4降低,rT_3升高,与对照组比较,有显著差异,P<0.01。血清T_3、T_4下降与多器官功能衰竭病人病情危重程度及受损害器官多少有密切关系。肝功能衰竭患者低T_3、低T_4尤为严重,与对照组比较有非常显著差异,P<0.001,且与死亡率有明显关系。这提示血清T_3、T_4浓度可作为判断多器官功能衰竭病人预后的一项指标。

The changes of the serum T_3,T_4 in 80 cases of multisystem organ failure (MSOF)and the rT_3 in 58 cases out of the 80 have been summed up in this paper. The results showed that in the cases of MSOF, the serum T_3, T_4 concen- tration decreased and rT_3 increased. There was significant differences (p<0.01) between the test group and the control group, The decrease of serum T_3 T_4 was related to teverity of the disease and the number of damaged organs in the MSOF cases. The serum T_3 and T_4 were obviously low in the patients with liver function failure and had a very significant difference (P<0.001) when com- pared with those of the control group. The low T_3 and T_4 were obviously related to tha mortality. This may suggesi that serum T_3, T_4 concentration may be regarded as a prognostic index for MSOF.