肝炎肝硬化患者血清纤维联结蛋白的变化与意义

The Variation of Serum Fibronectin and Its Significance in Patients with Post—Hepatitis Cirrhosis

采用单向免疫扩散法测定83例各型肝炎患者的血清纤维联结蛋白值,结果表明:急性肝炎组高于正常人组(P>0.5)。慢活肝组稍低于正常人组(P>0.5),重肝组与肝炎后肝硬化(失代偿)组均明显低于正常人组(P<0.001)。

The serum fibronectin(Fn)level was measured by the method of simple agar diffusion in83 patients with different types of hepatitis.The results show that fibronectin level was higher inacute hepatititis group than that in the normal subject group(P>0.5),slightly lower in chronicacute group than that in the normal subject group(P>0.5)and significantely lower in severehepatitis and post hepatitis cirrhosis(PHC)groups than that in the normal group(P<0.01). The quantitive estimation of this parameter has evaluative and prognostic value.