利培酮与舒必利对精神分裂症病人生活质量影响的双盲对照研究

A Double Blind Comparing Study between the Effects of Risperidone and Sulpiride on the Life Quality of the Patients with Schizophrenia.

目的 比较利培酮与舒必利对精神分裂症病人生活质量的影响。方法 行双盲对照研究及生活质量综合评定问卷( GQOLI)评估病人生活质量。结果 利培酮组的躯体健康维度 ,心理健康维度及社会功能维度分值明显高于舒必利组 ,均有显著性差异 ( P<0 .0 1 )。

Objective To compare the effect between risperidone and sulpiride on the life quality of the patients with schizophrenia.Methods The patients with shcizophrenia treated respectively by risperidone and sulpiride were in double blind compared with General Quality of Life Inventory(GQOLI).Result The risperidone group had the better effect than sulpiride group in the field of physical function,mental health and social function.The difference was significant(P<0.01).Conclusion The patients with schizophrenia treated by risperidone had better life quality than that of sulpiride.