卵巢上皮癌伴腹水术前化疗的作用和意义

Significance of Pre-operative Chemotherapy in Epithelial Ovarian Carcinoma Patients with Ascites

卵巢上皮癌伴腹水患者 34例 ,随机分为 2组。A组 :采用术前 PAC方案化疗加腹腔化疗 ,2～ 3个周期 ;B组 :单纯腹腔化疗 2周期。结果 :A组 2 2例患者经治疗后 ,完全缓解 (CR) 5例 ,部分缓解 (PR) 12例 ,无变化(NC) 5例。B组 12例患者经腹腔化疗后 CR0例 ,PR4例 ,NC8例。表明采用术前全身化疗和腹腔化疗相结合的方法 ,疗效较好 。

Thirty-four epithelial ovarian carcinoma (EOC) patients with ascites were divided into two groups: group A (n=22) receiving preoperative chemotherapy with PAC regimen plus abdominal cavity chemotherapy 2 or 3 cycles; group B (n=12) undergoing abdominal chemotherapy only 2 cycels. Results showed in the group A 5 of them were complete remission (CR ), 12 patients were partial remission (RP) and 5 no change (NC), while in the group B, CR was zero, 4 patients PR and 8 NC. It was concluded that pre-operative chemotherapy combined with abdominal chemotherapy is a valuable method in the treatment of the patients with EOC