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硝酸甘油经硬膜外导管鼻腔给药在小儿腭裂修补术的应用 被引量:3

Application of nitroglycerin by nasal carity in cleft palaterepairing surgery
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摘要 目的 减少小儿腭裂修补术中失血量。方法  36例患儿在气管内麻醉下行腭裂修补术 ,随机分成两组 ,A组术中将硬膜外导管插入健侧鼻腔 0 .5~ 1.0cm ,间断推注硝酸甘油 (NTG 1ml=1.0mg)降压 ;B组为对照组 ,观察术中血压、心率及失血情况。结果 A组术中SBP、DBP明显低于B组 (P <0 .0 1) ,而血红蛋白高于B组 (P <0 .0 5 )。结论 NTG经鼻给药降压 ,方法简单、安全、效果确切。 Objective To reduce blood loss in palate repairing surgery. Methods 36 patients with cleft palate were randomly divided into two groups.Group A received nitroglycerin(1 mg) intermitted by the normal nasal cavity with an epidural tube inserted into the cavity for controlled hypotension.Group B served as control group.The blood pressure,heart rate and blood loss volume were measured during operation.Results SBP and DBP in group A were lower singnificantly than those in group B(P<0.01),while haemoglobin in group A was higher than that in group B(P<0.05).Conclusion The controlled hypotension induced by the nasal administration of NTG could be an efficacious, simple and safe way to control blood loss in cleft palate repairing surgery.
出处 《安徽医学》 2002年第2期15-16,共2页 Anhui Medical Journal
关键词 手术 腭裂 硝酸甘油 失血 鼻腔给药 儿童 Surgery Cleft palate Blood loss Nitroglycerin
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参考文献2

  • 1盛卓人.实用临床麻醉学(第1版)[M].沈阳:辽宁科学技术出版社,1992.425.
  • 2黄东风 沈施仁.硝酸甘油滴鼻降压在动脉导管未闭结扎术的应用[J].临床麻醉学杂志,1997,5:320-320.

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