原发性胆汁性肝硬化的研究

Study on Primary Biliary Cirrhosis of Lver

探讨原发性胆汁性肝硬化(PBC)的研究现状 ,从流行病学调查、病因学、组织学、病理学等方面概述了PBC特征 ,目前临床多分为四期 :初期、无黄疸期、黄疸期、晚期 ,实验室检查AMA、ALP、AgM三者异常可确诊 ,熊去氧胆酸是治疗PBC的一线药物 ,大多与免疫抑制剂联合应用 。

Discuss the study situation of primary biliary cirrhosis(PBC).The features of PBC were expounded on epidemiological investigation,etiology,histology and pathology.At present,there are 4 stages:early stage,non jaundice stage,jaundice stage and late stage.It's defined from abnormal AMA,ALP and AGM in lab test.Ursodesoxycholicacid is the first medicine to treat PBC,which is often used with immune inhibitants.Liver transplantation is the only way to effectively treat late PBC.