联苯双酯、小柴胡汤联合治疗肝硬化病甲胎蛋白阳性者的临床观察及研究

Clinical effects and experimental study on treatment of hepatic cirrhosis's increasing patients of AFP with bifendate and sho-saiko-to

目的 观察联苯双酯 (DDB)、小柴胡汤 (SS)联合治疗肝硬化病甲胎蛋白阳性者的临床疗效并探讨其作用机理。方法 将 4 1例肝硬化病甲胎蛋白阳性者随机分为治疗组和对照组 ,治疗组在常规治疗的基础上服用DDB及SS加减 ,对照组仅采用常规治疗。结果 治疗组患者症状改善时间及甲胎蛋白值的下调 ,与对照组相比 ,有显著性差异 ,且未发现任何不良反应。结论 DDB及SS加减 。

Objectives To observe clinical effects of bifendate(DDB) and the herbal medicine sho-saiko-to(SS) in treating hepatic cirrhosis's increasing patients of AFP,the alteration of the lever of DDB and SS.Methods 41 cases suffered from hepatic cirrhosis by ultrasonography.20 patients which treated with DDB and SS in general treating basic were randomly divided into treated group.Results 14th day after DDB and SS treatment,AFP level were remarkably decreased and disease was significantly improved(P< 0.01). DDB and SS are effective and safe.Conclusions In treating hepatic cirrhosis and decreasing AFP,using DDB and SS improve the outcome of the patients.