中心型肥胖与胰岛素抵抗、2型糖尿病相关性探讨

Central Obesity with Insulin Resistance and Type 2 Diabetes

目的 探讨肥胖与胰岛素抵抗、2型糖尿病的相关性。方法 380 0名人群中 ,中心型肥胖者 342人为A组 ,外周型肥胖 2 2 8人为B组 ,32 30人非肥胖者为C组 (即对照组 )。分别计算RISI、IR、IGT、DM ,并进行统计学处理。结果 比较RISI,A组明显低于B组和C组 ,p <0 0 1;B组亦低于C组 ,p <0 0 5。各组间IR、IGT、DM发病率比较 ,A组、B组比C组明显增高 ,p <0 0 0 5 ;A组比B组IR、DM发病率明显增高 ,而IGT发生率虽比B组增高 (p <0 0 0 6 ) ,但无统计学意义 (p <0 0 5 )。结论 中心型肥胖者胰岛素抵抗、糖尿病发病率明显高于外周型肥胖和非肥胖者。

Objective Discussion of the relationship of obesity and insulin resistance,and relationship of obesity and type 2 diabetes.Mothods 3800 tested persons were divided in to three groups:the central obesity group A(342 person),and the peripheral obesity group B (228 persous),and the normal contral group C(3230pcrsous).Count RISI?IR?IGT?DM sespectively,and settle these datas with statistics.Results RISI in group A is significantly lower than groups B and C(p<0.01);group B was significantly lower than group C(p<0.05).The IR,IGT and DM in groups A and B was significantly higher than control group(group C)(p<0.05).The IR and DM rate in group A was significantly higher than group B.The IGT rate in group A is higher than group B,but it has no statistical significance(p>0.05).Conclusion The work suggested that the insulin resistance and diabetes in central obesity patients were higher than peripheral obesity patients and normal persons[