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乙肝病毒表面抗原(HBsAg)基因工程疫苗的研究进展 被引量:2

The Advances of the Genetic Engineering Vaccine of Hepatitis B Virus Surface Antigens(HBsAg)
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摘要 在乙肝病毒 (HBV)的结构蛋白中 ,与疫苗有关的主要是HBsAg。HBsAg基因已在不同的生物体系中获得成功的表达 ,其基因工程疫苗的研究也取得了长足的进展 。 In the structural proteins of hepatitis B virus (HBV), the protein which relates closely with vaccine is HBsAg. The genes of HBsAg have successfully expressed using different bio systems. Plasma derived vaccines (PDV) have been gradually replaced by yeast derived vaccines(YDV) and CHO derived vaccines.
出处 《药物生物技术》 CAS CSCD 2002年第1期53-56,共4页 Pharmaceutical Biotechnology
基金 浙江省科委重大科技项目( 99110 2 331)
关键词 乙型肝炎病毒表面抗原 基因表达 基因工程疫苗 HBV HBSAG Hepatitis B virus surface antigen (HBsAg ),Gene expression,Gene engineering vaccine
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