四逆温胆加减方治疗胆汁反流性胃炎32例临床观察

Clinical Observation on 32 Cases of Bile Reflux Gastritis by the Treatment of Sini and Wendan Added and Subtracted Decoction

目的:观察四逆温胆加减方治疗胆汁反流性胃炎的临床疗效。方法:将66例确诊为胆汁反流性胃炎的患者随机分为治疗组32例和对照组34例,治疗组给予四逆温胆加减方治疗,对照组给予西药多潘立酮(吗丁啉)、铝碳酸镁片(达喜)治疗,均以30天为1个疗程,观察两组患者治疗前后的临床疗效和胃镜下胆汁反流程度的变化,并进行统计分析。结果:治疗组总有效率90.6%,对照组总有效率73.5%,治疗组临床疗效、中医证候疗效、症状积分差值比较均优于对照组(P<0.05)。结论:四逆温胆加减方治疗胆汁反流性胃炎效果显著,值得临床推广应用。

Objective： To evaluate the clinical effect of orally taking Sini and Wendan Added and Subtracted Decoction to treat bile reflux gastritis. Methods： 66 cases of bile reflux gastritis patients were randomly divided into treatment group and con- trolled group. For the treatment group, 32 cases were orally given Sini and Wendan Added and Subtracted Decoction, while for the controlled group, 34 cases were orally given domperidone and hydrotalcid. Both types of treatment last a month to observe clinical symptoms and mucosal lesions before and after treatment. Results： For two groups, the total effective rate of the treat- ment group was 90. 6% ; the total effective rate of the controlled group was 73.5%. The treatment group was better than the con- trolled group in the clinical effe~：t, TCM syndrome effect, and score of symptoms （ P 〈0. 05 ）. Conclusions ： It has been proved that Sini and Wendan Added and Subtracted Decoction has a better curative effect to treat bile reflux gastritis.