无痛消化内镜检查术在COPDⅠ、Ⅱ级患者中应用安全性的临床研究

Safety and feasibility of Painless gastrointestinal endoscopy in patients with chronic obstructive pulmonary disease

目的探讨COPDⅠ、Ⅱ级患者行无痛消化内镜检查术的可行性、安全性,为建立无痛消化内镜检查规范提供临床依据。方法异丙酚联合小剂量芬太尼静脉镇静麻醉下,观察COPDⅠ、Ⅱ级患者行消化内镜检查术前、术中、术后血压、心率、血氧饱和度的变化,和术中、术后不适及并发症的发生情况。结果全部患者均完成无痛消化内镜检查,不良反应:包括舌后坠、呛咳躁动、血氧饱和度下降、心律失常、血压下降等,经合理处置后患者均完成全程检查。结论充分术前准备,严密监测术中不良反应并及时处理,COPDⅠ、Ⅱ级患者行无痛消化内镜检查术是可行的、安全的。

Objective To investigate safety and feasibility of Painless gastrointestinal endoscopy in patients with chronic oh struetive pulmonary disease of grade I , Ⅱ . Methods Propofol combined with low doses of fentanyl were used in painless gas- trointestinal endoscopy . Muhifunction monitor was used to measure systolic blood pressure （ SBP）, diastolic blood pressure （DBP） ,heart rate （HR） and blood oxygen saturation （SPO2 ） of patients before.after and during Painless gastrointestinal en- doscopy. Discomfort and complications was observed and recorded during and after operation. Results Painless gastrointestinal endoscopy was performed in all patients. Adverse reactions did not affect examination after reasonable disposal, including glos socoma, bucking and restlessness, decrease of oxygen saturation, arrhythmia, blood pressure drops, etc. Conclusion Painless gastrointestinal endoscopy is feasible and safe for patients with chronic obstructive pulmonary disease of grade I . Ⅱ through sufficient preparations before examination and observing adverse reactions closely and solving it timely during practice.