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Fas系统与系统性红斑狼疮

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摘要 系统性红斑狼疮(SLE)的发病机制是十分复杂的,通常认为是遗传、环境等多种因素综合作用的结果,各种因素相互作用引起B细胞功能亢进,多克隆激活而产生大量自身抗体,导致机体免疫调节功能紊乱.研究发现,细胞凋亡异常与SLE的发病存在明显的相关性,而Fas-FasL系统在细胞凋亡中起着非常重要的作用.本文对近年来Fas系统与SLE关系的研究作一简述.
出处 《职业与健康》 CAS 2002年第5期128-129,共2页 Occupation and Health
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