摘要
通过改进的 Pedersen方法合成了二苯并 -1 4-冠 -4,经硝化合成了二硝基二苯并 -1 4-冠 -4,然后用Pd/ C还原得到了二氨基二苯并 -1 4-冠 -4.中间体和产物的结构通过红外光谱和核磁共振等方法确证 .并通过1 H NMR、1 3C NMR和分子力学计算法研究了二氨基二苯并 -1 4-冠 -4的 2种异构体的空间结构 .结果表明 ,与其所示的化学结构相一致 ,存在顺、反
Cis and trans dinitrodibenzo 14 crown 4 were synthesized via nitration of dibenzo 14 crown 4(DB14C4D) synthesized by a modified Pedersen method. Cis and trans diaminodibenzo 14 crown 4 ( cis DAmDB14C4 and trans DAmDB14C4) were obtained by reduction of NO 2 group using Pd/C catalyst. All the compounds were characterized by NMR, IR and elemental analysis. The stereo structures of the cis and trans diaminodibenzo 14 crown 4 in DMSO have been investigated by 1H NMR , 13 C NMR and computer simulation.
出处
《应用化学》
CAS
CSCD
北大核心
2002年第4期329-333,共5页
Chinese Journal of Applied Chemistry
基金
国家自然科学基金 (2 99740 2 6)
河南省自然科学基金资助项目
