摘要
目的 本研究旨在以心率变异性 (HRV)为手段 ,探讨老年人心脏自主神经活动时相的生物学特征。 方法 共入选 2组健康受试者 :观察组 33例 ,年龄 65～ 82岁 ,平均 ( 72± 10 )岁 ;对照组 31例 ,2 6～ 35岁 ,平均 ( 30± 4)岁。对 2组对象进行 2 4h动态心电图监测 ,记录每小时HRV的频域指标 (总功率TP ,低频成分LF ,高频成分HF ,及LF/HF)。采用余弦拟合法对所得数据进行处理。 结果 HRV的频域指标呈典型的昼夜节律分布 ;与年轻组相比 ,老年人TP ,LF及HF的均值及振幅明显减低 ;LF/HF的振幅也减低 ,但其均值无显著变化。 2组间各指标的相位无明显变化。 结论 老年人HRV的 2 4h均值及昼夜波动振幅渐低 ,而其相位不变。
Objective To evaluate the effect of aging on the circadian variation of heart rate variability. Methods Two groups of healthy volunteers were included in this study:Group I,33 cases,aged 65～82(72±10)years;Group Ⅱ,31 cases,aged 26～35(30±4)years.HRV was assessed by 24 hours Holter recording,and cosinor fitting method was introduced to analyze the circadian. Results It was found that the mean value of TP,LF and HF and the swing of LF/HF cosinor curve decreased in the elder group,without any change in the average of LF/HF. Conclusions Aging process has a significant effect on autonomic nervous function of cardiovascular system.
出处
《实用老年医学》
CAS
2002年第2期82-84,共3页
Practical Geriatrics
基金
河北省科委资助课题 (编号 :982 761 88D与 992 761 1 71 )
