基因转录调控与早期三维生命体模式的构建

Formation of an Early Three-dimensional Embryonic Pattern is Dependent upon Gene Transcriptional Regulation

从分子生物学的角度而言 ,胚胎发育就是基因的时空调控过程 ,从而构建动物的三维模式 .顺式调控是发育基因的基本原理 ;转录调控因子的激活与抑制决定了细胞分化与结构形成 .

In the view of molecular biology on morphogeny of a three-dimensinal embryo, morphogenesis and development are dependent upon activation of transcription of involving genes followed by the inactivation in a specific part of embryo at a certain time. It has been demonstrated that cis-acting elements of genes can act to provide sharply defined patterns. Simultaneously, it is accepted as an important mechanism that both activation and repression of transcription factors are closely related to cell differentiation and morphogenesis.