摘要
胚胎着床受许多因素的精确调控,其中着床部位母体细胞的凋亡在围植入期执行着重要的生理任务。但它自身的发生机制尚不完全清楚,在胚胎着床中的调节机制就更远远落后于凋亡在其他系统领域中的相知程度。因此,对细胞凋亡在着床部位母体细胞中出现的深入研究;将进一步完善我们对着床机制的理解。同时,因为肿瘤与胚胎对机体作用的相似性也使这个领域的研究具有特殊的意义。
During embryo implantation, apoptosis is observed morphologically at the implantationsite of endometrium, in order to facilitate embryo anchorage and access to maternal blood supply.Dut our understanding of the cellular and molecular mechanisms regulating this process clearlylags behind the comprehension of cell death control in other systems. Mnybe we can understandthe mechanism of embryo implantation deeply by study apoptosis in uterine epithelial cells. Itis easy to find similarities between mammal embryo implantation and the spread mechanism oftumor cell in the body. So study the similarities between embryo and tumor become a breach tounderstand the life processes.
出处
《生命科学》
CSCD
2002年第2期70-72,121,共4页
Chinese Bulletin of Life Sciences
基金
基金项目:国家"九五"重点科技攻关项目 (9690-02-01)