曲马多 氟哌利多自控镇静镇痛术应用于耳鼻喉手术的临床观察

A clinical observation on self-controlled conscious-sedation of tramadol and droperidol in ENT surgery

目的 探讨曲马多、氟哌利多自控镇静镇痛术在耳鼻喉手术中效果及安全性。方法 将 2 0 0例耳鼻喉手术病人随机分成 2组 :曲马多、氟哌利多自控镇静镇痛组各 10 0例 ,患者局麻前 5min缓慢静脉注射氟哌利多0 0 5mg kg ,曲马多 2mg kg,并持续微量泵输入其混合液 2 4～ 36h ;对照组 10 0例 ,用目前常用麻醉方法 :局麻。结果 术中、术后镇静镇痛效果比较 ,两组比较差异有显著性 (P <0 0 1)。结论 曲马多、氟哌利多自控镇静镇痛术用于耳、鼻、喉手术安全。

Objective To observe the effect and safety of conscious sedation of tramadol and droperidol in ENT (ear.nose.throat) surgery.Methods Two humdred patients undergoing ENT surgery were individed into test group (group T, n =100) and comparative group (group C, n =100).Tramadol 2 mg/kg,droperidol 0 05 mg/kg were intravenously injected at 5 minutes before local anesthesia and droperidol was intravenously given continuonsly with micropump in 24～36 hours after the ENT surgery.Local anesthesia with dolantin was normally given in group C.Results During and after the ENT surgery,the effect of sedative analgesia in both groups was significantly different ( P <0 01),and SBP,DBP,HR was significantly different in both groups ( P <0 05),but SPO 2 has no significant difference ( P >0 05).Conclusion Conscious sedation of tramadol and droperidol is safe,effective in ENT surgery.