预防性肝动脉化疗栓塞对大肝癌切除术后生存率的影响

Influence of prophylactic transcatheter arterial chemotherapy and embolization (TACE) in the post-operative survival rate for large liver cancer.

目的 探讨预防性肝动脉化疗栓塞对大肝癌切除术后生存率的影响。 方法 对比分析术后预防性肝动脉化疗栓塞组 (观察组 ,32例 )及单纯对症支持治疗组 (对照组 ,17例 )的 1、3年生存率。 结果 观察组一年生存率 85 .5 % ,三年生存率 5 0 .8% ;对照组一年生存率 39.7% ,最长生存 14个月 ,差异显著 (P <0 .0 5 )。

Objective To study the influence of prophylactic transcatheter arterial chemotherapy and embolization (TACE) in the survival rate after hepatectomy for large liver cancer. Methods 49 cases of hepatectomy during last 4 years were divided into two groups: 32 cases treated with post-operative prophylactic TACE as the observation group, 17 cases with supportive therapy as the control group. Results 1 year and 3 years survival rate in the observation group were 85.5% and 50.8%, respectively; whereas 1 year survival rate in the control group was 39 7% and the longest survival in the control group was 14 months (P<0.05). Conclusion Prophylactic TACE after hepatectomy for large liver cancer significantly increases post-operative survival rate.