脑AVM的立体定向分次大剂量放射治疗临床追踪观察

Clinical Follow- up Observation of Cerebral AVM with Fractionated Stereotactic Radiotherapy (FSRT)

目的:探讨立体定向分次大剂量放射治疗AVM的疗效;方法:采用立体定向分次大量剂量直线加速器照射方法(FSRT)对40例脑AVM行治疗前后对照的临床追踪观察;结果:经18～66随访40例中两大脑半球AVM30例,18例畸形血管团缩小,10例变化不明显,2例死亡,脑干AVM7例、死亡3例,1例残疾;结论:FSRT技术可作为HSD技术的补充对深在重要功能区AVM可首先考虑使用。

Objective: The purpose of this Clinical Mow - up observation is to evaluate the efficacy FSRT. in treatment of the cerebral AVM. Methods: Forty patient with cerebral AVM were treated with FSRT, aged 12- 50 years (average 31.7), From 1995 to 2001 follow-up 18 - 66 months (average38.8). 30 patients with the bilateral cerebral hemisphere AVM, 3 pontine AVM. 4 mesenc-cphalic AVM,4 mesenceplialio AVM 4 cerebellar hemisphere AVM. Result: Out of thirty cases, eighteen (60%)cerebral hemisphere AVM have been shrinked, 10 cases (33.3% ) have no change. 2 cases dead, 4paticnts with mesencephlic AVM,3 eases dead and 3ccreb - ellar hemisphere AVM have no clinical presentation of brain stem edema and cerebellar dysfunction, in association with FS-RT. Conclusion: As for deepth and important functional region intracerebral AVM. We should take into account to using FSRT, and it may to be a method of the supplementary therapy of HSD.