120例乙肝病人循环免疫复合物的检测

Detection of circulating immune complex in 120 patients with viral hepatitis B

目的 探讨循环免疫复合物 (CIC)在乙肝发病机制上的作用。方法 应用聚乙二醇 (PEG)沉淀试验对 1 2 0例乙肝病人和 1 2 0例正常人群进行了循环免疫复合物检测。结果 乙肝病人CIC的阳性率达49 2 % ,正常人群CIC阳性率仅为 1 1 7% ,两者比较差异有非常显著意义 (P <0 0 0 5)。

Objective To investigate the effect of circulating immune complex(CIC) on the pathogenesis of viral hepatitis B.Methods Polyethylene glycol(PEG) precipitation test was used to detect the circulating immune complex in 120 cases of hepatitis B patients and 120 healthy controls.Results The positive rate of CIC was 49.2% in hepatitis B patients,and only 11.7% in healthy controls,by comparison,there are significance difference(P<0.005).Conclusion CIC plays an important role in the immuno pathologic injury of viral hepatitis B.