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食物防癌剂——吲哚-3-甲醇的研究进展 被引量:4

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出处 《中国基层医药》 CAS 2002年第3期268-269,共2页 Chinese Journal of Primary Medicine and Pharmacy
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  • 2N.Takahashi,RH Dashwood,LF Bjeldaness,et al.Mechanisms of indole-3-carbinol(I3C) anticarcinogenesis:Inhibition of aflatoxin B1-DNA adduction and mutagenesis by I3C acid condensation products.Fd Chem.Toxic,1995,33(10):851~857
  • 3N.Takahashi,DM Stresser,DE Williams,et al.Induction of hepatic CYP1A by indole-3-carbinol in protection against aflatoxin B1 hepatocarcinogenesis in rainbow trout.Fd Chem.Toxic,1995,33(10):841~850
  • 4Morse MA,La Greca SD,Amin SG,et al.Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone(NNK) and on the metabolism and disposition of NNK in A/J mice.Cancer Research,1990,50(9):2613~2617
  • 5Telang NT,Katdare M,Bradlow HL,et al.Inhibition of proliferation and modulation of estradiol metabolism:Novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol.Proc soc exp biol med,1997,216(2):246~252
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  • 7Michnovicz JJ.Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol.International Journal of Obesity,1998,22(3):227~229
  • 8Cover CM,Hsieh SJ,Tran SH,et al.Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G-1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.Journal of Biological Chemistry,1998,273(7):3838~3847
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  • 10Kelly VP,Ellis EM,Manson MM,et al.Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin,a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase,the glutathione S-transferase A5 and P1 subunits,and NAD(P)H:quinone oxidoreductase in rat liver.Cancer Res,2000,60(4):957~969

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